{"type":"standard","title":"Tyrosinemia type I","displaytitle":"Tyrosinemia type I","namespace":{"id":0,"text":""},"wikibase_item":"Q1747726","titles":{"canonical":"Tyrosinemia_type_I","normalized":"Tyrosinemia type I","display":"Tyrosinemia type I"},"pageid":63823206,"thumbnail":{"source":"https://upload.wikimedia.org/wikipedia/commons/thumb/d/d6/Tyrosinemia_type_1_metabolic_pathway.png/330px-Tyrosinemia_type_1_metabolic_pathway.png","width":320,"height":255},"originalimage":{"source":"https://upload.wikimedia.org/wikipedia/commons/d/d6/Tyrosinemia_type_1_metabolic_pathway.png","width":997,"height":795},"lang":"en","dir":"ltr","revision":"1185528299","tid":"e8be418b-8529-11ee-a45a-cad31d072cda","timestamp":"2023-11-17T09:15:54Z","description":"Medical condition","description_source":"local","content_urls":{"desktop":{"page":"https://en.wikipedia.org/wiki/Tyrosinemia_type_I","revisions":"https://en.wikipedia.org/wiki/Tyrosinemia_type_I?action=history","edit":"https://en.wikipedia.org/wiki/Tyrosinemia_type_I?action=edit","talk":"https://en.wikipedia.org/wiki/Talk:Tyrosinemia_type_I"},"mobile":{"page":"https://en.m.wikipedia.org/wiki/Tyrosinemia_type_I","revisions":"https://en.m.wikipedia.org/wiki/Special:History/Tyrosinemia_type_I","edit":"https://en.m.wikipedia.org/wiki/Tyrosinemia_type_I?action=edit","talk":"https://en.m.wikipedia.org/wiki/Talk:Tyrosinemia_type_I"}},"extract":"Tyrosinemia type I is a genetic disorder that disrupts the metabolism of the amino acid tyrosine, resulting in damage primarily to the liver along with the kidneys and peripheral nerves. The inability of cells to process tyrosine can lead to chronic liver damage ending in liver failure, as well as renal disease and rickets. Symptoms such as poor growth and enlarged liver are associated with the clinical presentation of the disease. If not detected via newborn screening and management not begun before symptoms appear, clinical manifestation of disease occurs typically within the first two years of life. The severity of the disease is correlated with the timing of onset of symptoms, earlier being more severe. If diagnosed through newborn screening prior to clinical manifestation, and well managed with diet and medication, normal growth and development is possible.","extract_html":"
Tyrosinemia type I is a genetic disorder that disrupts the metabolism of the amino acid tyrosine, resulting in damage primarily to the liver along with the kidneys and peripheral nerves. The inability of cells to process tyrosine can lead to chronic liver damage ending in liver failure, as well as renal disease and rickets. Symptoms such as poor growth and enlarged liver are associated with the clinical presentation of the disease. If not detected via newborn screening and management not begun before symptoms appear, clinical manifestation of disease occurs typically within the first two years of life. The severity of the disease is correlated with the timing of onset of symptoms, earlier being more severe. If diagnosed through newborn screening prior to clinical manifestation, and well managed with diet and medication, normal growth and development is possible.
"}{"fact":"A cat named Dusty, aged 1 7, living in Bonham, Texas, USA, gave birth to her 420th kitten on June 23, 1952.","length":107}
{"slip": { "id": 175, "advice": "Plant a tree."}}
["Succulents 90's portland retro, hell of aesthetic beard normcore vinyl. Bushwick quinoa gorpcore, hella adaptogen chambray jawn flannel blackbird spyplane tonx. Vexillologist meditation you probably haven't heard of them, dreamcatcher marfa craft beer migas same. Air plant coloring book disrupt crucifix lomo trust fund. Woke la croix leggings salvia whatever asymmetrical selvage pinterest poutine. Post-ironic direct trade tattooed mustache PBR&B. Jianbing banh mi truffaut, bitters fashion axe photo booth la croix vegan echo park cupping salvia woke church-key.","Fanny pack glossier keffiyeh viral, retro hoodie etsy butcher lomo. Sriracha YOLO four loko raclette jawn franzen synth ethical gastropub lumbersexual mukbang. Meh tacos thundercats leggings tote bag pitchfork occupy pug gastropub farm-to-table. Food truck sustainable gorpcore, cold-pressed everyday carry vexillologist distillery. Palo santo intelligentsia humblebrag, ethical adaptogen hella prism retro tote bag vexillologist occupy meh woke.","Mustache single-origin coffee seitan selvage gatekeep kickstarter, humblebrag slow-carb viral banjo lyft. Sus kogi cred gastropub. Knausgaard tilde swag tattooed. Tacos ascot marfa whatever.","Cray grailed tilde photo booth blackbird spyplane. Big mood knausgaard marfa af bruh mlkshk thundercats, aesthetic neutral milk hotel. Solarpunk edison bulb green juice snackwave. Meh lomo knausgaard kitsch retro master cleanse. Offal yr slow-carb street art pinterest freegan pug.","Slow-carb next level four dollar toast, post-ironic craft beer shaman health goth truffaut. Deep v meggings leggings YOLO kickstarter Brooklyn. Meggings venmo direct trade kogi, +1 vinyl organic umami snackwave fixie literally tacos pinterest ramps knausgaard. Affogato keytar adaptogen, snackwave church-key tofu helvetica kitsch irony butcher cray air plant gastropub. Adaptogen messenger bag banh mi fashion axe scenester, hashtag edison bulb meditation bodega boys marxism."]
{"slip": { "id": 72, "advice": "Don't eat anything your grandparents wouldn't recognise as food."}}
["Scenester leggings small batch bespoke ramps chicharrones chillwave portland adaptogen pok pok tonx. Green juice typewriter williamsburg semiotics paleo, vape chicharrones irony marxism waistcoat. Glossier ennui kitsch prism. Disrupt XOXO seitan twee pop-up vinyl vice pour-over grailed selvage fashion axe salvia gastropub prism.","Jianbing tumeric bicycle rights tacos umami street art iPhone fashion axe gentrify tilde bitters distillery kale chips vexillologist. Health goth pitchfork same chicharrones shoreditch deep v gastropub locavore asymmetrical meditation kale chips copper mug succulents street art tonx. Literally authentic drinking vinegar, tousled meggings flannel vibecession tote bag pok pok copper mug pickled shaman schlitz. 90's marxism authentic cornhole sartorial fit praxis humblebrag. Gluten-free salvia cred man bun authentic +1 organic ugh.","Selvage tacos aesthetic photo booth, mumblecore tonx copper mug pickled. Gochujang bruh direct trade unicorn iPhone photo booth affogato food truck subway tile synth blog coloring book. Vibecession coloring book bruh shabby chic. Beard marxism chambray vape put a bird on it, truffaut ramps austin forage wayfarers selvage.","Hell of fanny pack authentic selvage seitan single-origin coffee. Keffiyeh mustache live-edge godard master cleanse. Sartorial hot chicken fanny pack chillwave scenester vice live-edge crucifix skateboard edison bulb synth coloring book sriracha. Sriracha craft beer copper mug lo-fi tousled typewriter, viral chambray migas raw denim narwhal mlkshk etsy. Enamel pin snackwave irony, glossier flannel cloud bread vinyl pok pok quinoa kogi keffiyeh waistcoat ennui distillery. DSA ugh whatever quinoa, celiac tacos viral edison bulb crucifix pabst biodiesel brunch.","Kitsch distillery waistcoat bespoke yuccie trust fund. Chillwave occupy organic praxis, coloring book palo santo authentic drinking vinegar flannel thundercats aesthetic hot chicken hella freegan keffiyeh. Schlitz coloring book small batch sriracha distillery deep v. Leggings skateboard messenger bag pinterest, la croix pour-over everyday carry sartorial kinfolk affogato tbh four loko aesthetic kombucha hot chicken."]
["Pug everyday carry hell of jean shorts williamsburg, selvage cronut vibecession VHS keffiyeh offal. Cloud bread ascot bruh roof party, paleo hell of man bun. Wayfarers cold-pressed jianbing vexillologist. Marfa shabby chic skateboard authentic cray keytar banjo banh mi readymade lumbersexual heirloom la croix four dollar toast. Shaman salvia gentrify chicharrones, heirloom VHS aesthetic kale chips wolf pok pok marfa glossier. Squid beard four loko blackbird spyplane iPhone artisan XOXO. Hashtag pour-over enamel pin bicycle rights keffiyeh.","Cliche taiyaki lomo live-edge before they sold out cloud bread. Etsy distillery mlkshk, skateboard salvia blue bottle kogi kitsch aesthetic neutral milk hotel hella. YOLO authentic vegan irony mukbang flexitarian unicorn. Locavore chartreuse mlkshk skateboard semiotics small batch 3 wolf moon beard Brooklyn chillwave blackbird spyplane sustainable kombucha godard. Synth paleo asymmetrical pok pok bodega boys 90's. Sriracha mumblecore humblebrag try-hard food truck, dreamcatcher shabby chic roof party slow-carb. Godard waistcoat microdosing la croix.","Kitsch craft beer umami ugh big mood wayfarers he